Identification of a Novel Glycoside, Leptosin, as a Chemical Marker of Manuka Honey

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Identification of a novel glycoside, leptosin, as a chemical marker of manuka honey.

As a preliminary study, we have found that honey from manuka (Leptospermum scoparium) in New Zealand inhibits myeloperoxidase (MPO) activity. In this study, using a chromatographic technique, we isolated two active compounds for MPO-inhibition from manuka honey. One is methyl syringate (MSYR), and the other was identified as a novel glycoside of MSYR, methyl syringate 4-O-β-D-gentiobiose, which...

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Immunochemical authentication of manuka honey using a monoclonal antibody specific to a glycoside of methyl syringate.

Leptosperin, a novel glycoside of methyl syringate, is exclusively present in manuka honey derived from the Leptospermum species Leptospermum scoparium. Quantification of leptosperin might thus be applicable for authentication of honey. The concentration of leptosperin has high linearity with antibacterial activity. We established a monoclonal antibody to leptosperin and characterized the antib...

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ژورنال

عنوان ژورنال: Journal of Agricultural and Food Chemistry

سال: 2012

ISSN: 0021-8561,1520-5118

DOI: 10.1021/jf300068w